Immature Platelet Fraction (IPF)
Patient IPF

Advanced Clinical Parameters (ACPs) for Laboratorians: IPF 

Utilizing fluorescent flow cytometry and specialized dyes, the Immature Platelet Fraction is a direct cellular indicator of thrombopoietic activity and may aid physicians in assessing and monitoring thrombocytopenias.


Watch: A pediatric hematologist's perspective

Our Advanced Clinical Parameters (ACPs) expand the routine CBC beyond traditional use and may assist clinicians with patient care. Dr. Kandace Gollomp, pediatric hematologist/oncologist at the Children's Hospital of Philadelphia, explains how Sysmex's Reticulocyte Hemoglobin Equivalent (RET-He) and Immature Platelet Fraction (IPF) can be used to help determine a patient's underlying condition, even when other parameters may be unreliable. Dr. Gollomp describes how Reticulocyte Hemoglobin Equivalent (RET-He) and Immature Platelet Fraction (IPF) can be included in order sets or as reflex testing, and how she encourages other specialists in her hospital system to incorporate Sysmex's ACPs as part of their patient workups..

  • The Role of the Immature Platelet Fraction (IPF) in the Differential Diagnosis of Thrombocytopenia

    The Immature Platelet Fraction (IPF%) and the Immature Platelet Fraction Count (IPF#) may help physicians better understand the pathophysiological mechanisms leading to low platelet counts.
    Read White Paper
  • Read (abstract): The immature platelet fraction: creating neonatal reference intervals and using these to categorize neonatal thrombocytopenias

    The immature platelet fraction (IPF) is a laboratory measurement analogous to the reticulocyte count, but reflecting the thrombopoietic state. It can be expressed as a percent (IPF%=percent of platelets that are immature) or as an absolute number per μl blood; the immature platelet count (IPC=IPF% × platelets per μl of blood).
    Read Abstract
  • Hematopathologist's Perspective of Immature Platelet Fraction

    Reporting Sysmex's Immature Platelet Count (IPF) as a reflex test in thrombocytopenic patients related to consumptive vs. productive causes of thrombocytopenia.
    Watch Video

Watch: Getting More From the CBC: IPF and Other Innovative CBC Parameters

The Immature Platelet Fraction (IPF) and absolute immature platelet may be used to assist clinicians with thrombocytopenic patients.